To support this transformation, Mathematica leverages its expertise in measurement science, deep understanding of CMS quality programs, and clinical care subject matter experts to develop, test, and maintain measures for use in quality improvement and quality reporting and payment programs. We focus on developing measures with a strong evidence base and the greatest potential to drive quality improvement, with an emphasis on risk-adjusted outcome measures and patient-reported outcome-measures (PRO-PMs).Mathematica develops digital quality measures using the Fast Health Interoperability Resources standard. We ensure that the voice of the patient is an active part of the development process, relying on patient and family advisory boards to provide feedback and share their unique lived experience to shape measures that matter.
Mathematica is a trusted partner in measure development and maintenance for the Centers for Medicare & Medicaid Services (CMS), federal agencies, medical specialty societies, foundations, and medical device manufacturers. As a leader in this space, we contribute thought leadership and deep technical expertise through ongoing engagement with CMS's Consensus-Based Entity (CBE). Our staff actively serve on CBE's Endorsement and Maintenance Panels as well as its Scientific Methods Panel, ensuring we remain at the forefront of evolving measurement standards. We have also led technical expert work groups dedicated to advancing standards for electronic clinical quality measures (eCQMs) and the development of patient-reported outcome performance measures (PRO-PMs).
Evidence & Insights

Streamlining Performance Measures for More Effective Value-Based Care
In a new Health Affairs Forefront article, Mathematica experts share how healthcare payers can build a cohesive measure set that fosters more effective, efficient, and accountable value-based care programs.
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Clinical Quality Measure Development
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